Research and innovation


The NIHR Clinical Research Network (CLRN) performs the principal function of connecting researchers throughout the country to a central funding body for clinical research and provides the infrastructure for designing and conducting research. It acts to both disseminate research priorities and also to distribute resources for supporting high-quality research.

There is currently an active focus on:

  • medical retina conditions (age-related macular degeneration and conditions caused by diabetes)
  • ocular inflammation
  • neuro-ophthalmology.

Researchers may apply to participate in portfolio-accepted studies, which are managed by CLRN hubs throughout the UK.

International clinical trials networks

The Diabetic Retinopathy Clinical Research Network ( is a principally North American research network. Research datasets on its webpages are available to researchers.

The Neuro-Ophthalmology Research Disease Investigator Consortium (NORDIC) is a platform for organising and collaborating on North American neuro-ophthalmology clinical trials.

The International Uveitis Society Study Group

The Standardization of Uveitis Nomenclature (SUN) Working Group is part of this group of research leaders in uveitis. Ocular Immunology and Inflammation is the official journal of the International Uveitis Study Group.


The Biologics Ocular Inflammation Surveillance Registry for Ocular inflammation, based at Bristol Eye Hospital, collects data from patients who receive biologic therapy. Currently the data are not publicly available and are being collected for a long-term prospective longitudinal study.